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User experimentation suggests that longer initial treatment periods (6+ months continuous) support better benefit retention during subsequent breaks, complete discontinuation breaks of 1-2 months show acceptable benefit maintenance for most users, and very extended breaks (3-6+ months) increase risk of regression toward pre-treatment baseline particularly for short initial treatment courses
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Fulfillment Location:UK
These authors also demonstrated that 10 mg/kg bw/day of NAC given to fructose-fed SD rats in drinking water for nine weeks prevented an increase in serum and adipose tissue methylglyoxal levels, and improved glucose uptake (131)
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