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mTORC1 is also known to favor translation of TOP (terminal oligopyrimidine tract) mRNAs, which bear a 5β² oligopyrimidine sequence downstream of the N 7 -methyl guanosine triphosphate cap, present in most ribosomal mRNAs (Levy et al., 1991
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In this review, we describe the metabolic transformation in cancer cells, then summarize different roles of glutamine in cancer metabolism in biosynthesis and stress protection
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